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Calculates partition coefficients describing how substances distribute between immiscible liquid phases.
Formel
Kp = [Solute in Phase A] / [Solute in Phase B]
Trinn-for-trinn guide
- 1Enter equilibrium concentrations in each phase
- 2Calculate the ratio of concentrations
- 3Interpret distribution preference
Løste eksempler
Inndata
Drug concentration: 50 mg/mL water, 200 mg/mL octanol
Resultat
Kp = 0.25 (prefers water)
Drug solubility distribution
Vanlige feil å unngå
- ✕Reversing phase concentrations
- ✕Confusing with distribution ratio for ionic species
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